Direct sulfonylation of anilines mediated by visible light

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Direct sulfonylation of anilines mediated by visible light† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc03891g

Sulfones feature prominently in biologically active molecules and are key functional groups for organic synthesis. We report a mild, photoredox-catalyzed reaction for sulfonylation of aniline derivatives with sulfinate salts, and demonstrate the utility of the method by the late-stage functionalization of drugs. Key features of the method are the straightforward generation of sulfonyl radicals ...

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ژورنال

عنوان ژورنال: Chemical Science

سال: 2018

ISSN: 2041-6520,2041-6539

DOI: 10.1039/c7sc03891g